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Founded in 2008 in New York City, La4ve Diamonds has been fortunate to have been among many happily ever afters. We understand the gravity of our role in making your special moments the highlights of every stage of your love story.
We are family owned and operated, and with that, our personalized communication, attention to detail, and unrivalled expertise is what sets us apart. We pride ourselves on being an elegant one-stop shop for bridal and fashion jewelry. Our artisans work tirelessly to create a diverse catalog of items perfect for any occasion.
La4ve Diamonds sets the stage for love, as we realize that love is eternal. We appoint it our duty and personal pledge to preserve high quality standards and fabricate our collection as a symbol of the eternal bond of love.
At La4ve Diamonds, we realize your vision with the best quality craftsmanship. Working in the age old art of lost wax casting, our artisans apply their traditional skills and techniques to produce an heirloom masterpiece.
Additionally, we specialize in the use of cutting edge technology in manufacturing jewelry, so that the end result is a quality product at the highest standards.
Once production is complete, all items are reviewed by our in-house GIA Graduate Gemologist staff. We stand firmly by all product disclosures, as we know the importance of this purchase to you.
La4ve Diamonds items feature only conflict-free diamonds that are ethically sourced from mines abiding by strict labor and trade laws, as well as adhering to the latest environmental standards. We source and provide only natural diamonds and hold the highest standards in assuring the quality and integrity of our diamonds.
In addition to strict adherence to the Kimberley Process Certification System, a UN-backed practice that certifies that origins of our diamonds are from sources free of conflict and acquired through friendly mining, we are also members of Responsible Jewelry Council.
At La4ve Diamonds, with excellence as our benchmark, our products are made of the highest quality materials. Our team of skilled artisans use a combination of traditional goldsmithery and modern technology to create an heirloom piece which, is not only unique in its design, but timeless in nature.
At La4ve Diamonds, we follow rigorous quality control standards and each product is carefully inspected to adhere to strict quality standards and evaluated by our in-house GIA Graduate Gemologist, who has decades of experience in the diamond and jewelry industry.
At La4ve Diamonds, we stand by the quality of our products. As a family-owned and operated business, we take our product integrity seriously. Generations of diamond and production experts have helped shape our brand, and we are always searching for new and innovative techniques to advance our future product offerings.
Molecular pathway of estrogen receptor (ER) action. Typically, estrogen binds to the ligand-binding domain of receptors in the nucleus, which causes a conformational change. Estrogen-responsive elements (ERE) mediate genomic effects. RE, response element; TF, transcription factor; GF, growth factor; GF-R, growth factor receptor; CoA, co-activator; CoR, co-repressor; MAPK, mictogen-activated protein kinase; PI3K, phophoinositide 3-kinase; Src, proto-oncogene tyrosine-protein kinase; AP-1, activating protein-1; Sp-1, stimulating protein-1. Adapted from Nie et al.16
Measurement parameters utilized to determine the esophageal motor function. (A) Esophagogastric junction (EGJ). (B) Esophageal body. EGJ-CI, esophagogastric junction-contractile integral; IRP, integrated relaxation pressure; LES, lower esophageal sphincter.
High-resolution manometry test swallows and maneuvers. (A) Supine 5 mL liquid; (B) upright 5 mL liquid; (C) viscous (apple sauce); (D) solid (graham cracker); (E) multiple rapid swallow; and (F) rapid drink challenge. Integrated relaxation pressure (IRP) and distal contractile integral (DCI) were 11 mmHg and 1760 mmHg·cm·sec (A), 8 mmHg and 1950 mmHg·cm·sec (B), 7 mmHg and 1600 mmHg·cm·sec (C), 10 mmHg and 1400 mmHg·cm·sec (D), 4 mmHg and 4600 mmHg·cm·sec (E), and 3 mmHg and 0 mmHg·cm·sec (F), respectively. Figure used with permission from the Esophageal Center at Northwestern.
Our diagnostic algorithm of defecation disorders using a colonic transit study. DD, defecation disorders; DRE, digital rectal examination; NTC, normal transit constipation; STC, slow transit constipation; RS, rectosigmoid colon.
Statistical maps showing voxel-mirrored homotopic connectivity (VMHC) differences between irritable bowel syndrome (IBS) and healthy controls (HCs;